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. 2020 Jun 4;12(11):10290–10299. doi: 10.18632/aging.103248

Table 2. MTHFR C677T allele and genotype frequencies in male and female of schizophrenia and healthy controls.

Variable SCZ (n=957) Controls (n=576) F or χ2 (p)
C677T genotype 2.0(0.36)
CC (%) 298(38.9) 145(34.8)
CT (%) 344(45.0) 202(48.4)
TT (%) 123(16.1) 70(16.8)
Male (CC/CT/TT) 7.6(0.023)
CC (%) 101(15.8) 31(18.7)
CT (%) 280(43.7) 87(52.4)
TT (%) 260(40.5) 48(28.9)
Female (CC/CT/TT) 2.3(0.32)
CC (%) 22(17.7) 38(15.3)
CT (%) 64(51.6) 115(46.2)
TT (%) 38(30.6) 96(38.5)
C677T allele (C/T) 590/940 342/492 0.08(0.83)
Male (C/T) 482/800 149/183 5.9(0.015)
Female (C/T) 108/140 191/307 1.9(0.17)