Table 2. MTHFR C677T allele and genotype frequencies in male and female of schizophrenia and healthy controls.
Variable | SCZ (n=957) | Controls (n=576) | F or χ2 (p) |
C677T genotype | 2.0(0.36) | ||
CC (%) | 298(38.9) | 145(34.8) | |
CT (%) | 344(45.0) | 202(48.4) | |
TT (%) | 123(16.1) | 70(16.8) | |
Male (CC/CT/TT) | 7.6(0.023) | ||
CC (%) | 101(15.8) | 31(18.7) | |
CT (%) | 280(43.7) | 87(52.4) | |
TT (%) | 260(40.5) | 48(28.9) | |
Female (CC/CT/TT) | 2.3(0.32) | ||
CC (%) | 22(17.7) | 38(15.3) | |
CT (%) | 64(51.6) | 115(46.2) | |
TT (%) | 38(30.6) | 96(38.5) | |
C677T allele (C/T) | 590/940 | 342/492 | 0.08(0.83) |
Male (C/T) | 482/800 | 149/183 | 5.9(0.015) |
Female (C/T) | 108/140 | 191/307 | 1.9(0.17) |