Table 3. Sex differences of clinical symptoms and cognitive functions in the patients with schizophrenia and healthy controls.

	Male			Female			Sex p	Genotype p	Sex×gene p
	TT	CT	CC	TT	CT	CC
Patients with SCZ
Cognitive functions
Immediate memory	56.3±14.5	58.0±15.7	58.4±16.8	64.0±13.9	68.8±22.9	58.7±13.9	0.017	0.06	0.05
Visuospatial/constructional	75.3±17.9	76.5±18.2	78.0±20.1	81.0±18.1	83.9±19.1	84.9±22.3	0.010	0.58	0.95
Language	81.0±14.6	80.7±15.4	80.3±16.6	83.3±16.3	88.9±15.8	80.7±15.0	0.084	0.23	0.24
Attention	67.5±17.3	70.0±16.7	71.1±18.6	83.0±15.2	78.3±17.1	71.5±17.8	0.001	0.46	0.05
Delayed memory	62.3±17.7	67.2±19.1	65.0±19.2	76.4±20.3	79.3±23.0	67.9±17.4	<0.001	0.04	0.26
Total score	61.7±13.4	63.5±14.6	64.4±14.8	71.8±14.4	75.0±19.0	65.9±14.9	<0.001	0.22	0.14
Clinical symptoms
Positive symptom	11.2±4.5	11.1±4.6	11.5±4.4	13.2±5.6	14.9±6.6	14.0±6.7	<0.001	0.37	0.24
Negative symptom	23.5±8.0	23.7±8.2	23.2±8.0	23.2±7.3	18.2±9.0	21.0±8.1	0.002	0.031	0.015
General psychopathology	25.0±5.5	24.7±5.6	25.5±6.2	28.8±6.3	27.4±5.6	28.8±8.5	<0.001	0.27	0.72
PANSS total score	59.7±14.5	59.5±14.6	60.2±14.7	65.2±14.6	60.5±14.8	63.7±19.4	0.04	0.29	0.39
Healthy controls
Cognitive functions
Immediate memory	74.9±17.0	76.2±15.3	74.4±15.7	73.3±17.3	77.8±18.3	74.6±20.0	0.97	0.32	0.74
Visuospatial/constructional	80.4±15.1	82.1±16.6	80.3±14.7	77.1±14.9	79.7±16.9	77.4±12.2	0.11	0.44	0.97
Language	95.2±9.1	94.0±12.0	97.5±13.4	93.0±14.1	93.3±13.3	92.3±16.5	0.08	0.80	0.48
Attention	87.5±21.0	90.5±16.3	87.9±20.5	83.5±22.0	85.9±22.4	92.9±15.6	0.61	0.27	0.24
Delayed memory	89.2±12.5	84.7±14.4	88.7±15.5	85.0±16.1	87.1±16.3	85.6±14.5	0.31	0.79	0.12
Total score	80.6±13.6	81.1±13.1	81.9±15.2	77.5±15.9	80.2±16.6	80.0±15.1	0.26	0.60	0.83