Table 2C. eQTL variants in the TMPRSS2 gene in different populations.

Variant ID	P GTEx	NES GTEx	Freq ITA	Freq EUR	Freq EAS	ITA vs EUR	ITA vs EAS	EUR vs EAS
rs463727	5.0e-10	0.12	0.44	0.46	0.0051	P=0.038	P<2.2e-16	P<2.2e-16
rs2070788	8.9e-9	-0.11	0.55	0.53	0.66	P=0.003	P=4.7e-15	P<2.2e-16
rs9974589	7.4e-9	-0.12	0.55	0.53	0.66	P=0.002	P=3.3e-15	P<2.2e-16
rs34624090	9.2e-9	0.12	0.43	0.45	0.0051	P=0.005	P<2.2e-16	P<2.2e-16
rs7364083	3.3e-9	-0.12	0.56	0.53	0.65	P=8.7e-05	P=1.9e-10	P<2.2e-16
rs55964536	1.9e-9	0.12	0.46	0.49	0.0045	P=4.6e-04	P<2.2e-16	P<2.2e-16
rs734056	1.3e-9	0.12	0.47	0.49	0.0051	P=0.030	P<2.2e-16	P<2.2e-16
rs4290734	8.3e-10	0.12	0.47	0.49	0.0051	P=0.019	P<2.2e-16	P<2.2e-16
rs34783969	3.9e-10	0.12	0.47	0.49	0.0051	P=0.027	P<2.2e-16	P<2.2e-16
rs11702475	8.4e-10	0.12	0.47	0.49	0.0046	P=0.015	P<2.2e-16	P<2.2e-16
rs35899679	7.8e-9	0.11	0.44	0.46	0.0051	P=0.004	P<2.2e-16	P<2.2e-16
rs35041537	3.6e-9	0.12	0.44	0.47	0.0051	P=8.6e-04	P<2.2e-16	P<2.2e-16

P values are presented as non-corrected; the number of statistical comparisons performed in Table 2C is collectively of 36, thus lowering the threshold for significance at P=0.0013 (Bonferroni threshold). Significant P values are indicated in bold.

NES: normalized effect size; Freq: frequency of the minor allele; ITA: Italian population; EUR: European population; EAS: East Asian population.