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Effect of QAE on renal AMPK/SIRT1 signaling in T2DM mice. (A) Phosphorylation of AMPK and (B) SIRT-1 and PGC-1α. Data were expressed as means ± SEM. Mean values with the same superscript letter (a,b) are not significantly different (p < 0.05). NC: Normal mice; DMC: Type 2 diabetic mice; LQ: Type 2 diabetic mice supplemented with a low dose (5 mg/kg/day) of QAE; HQ: Type 2 diabetic mice supplemented with a high dose (10 mg/kg/day) of QAE.
