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Effect of E3330 on the invasiveness of cisplatin-treated H1975 cells. (A) Transwell chemoinvasion was assessed after a pre-incubation period of 3 h with E3330 and a subsequent period of 16 h with both compounds. Values represent mean ± SD (n = 5) and are expressed as percentages relative to vehicle-treated control cells; * p < 0.05 and ** p < 0.01 (Student’s t-test). (B) Representative microscopy images of invading cells stained with crystal violet (100×). Scale bars = 100 μm.
