Figure 6.

ESC prevents the ROS formation induced by OAβ_1–42 in SH-SY5Y cells. (A) Cells were treated with ESC (20 µM) for 24 h and then with OAβ_1–42 (10 µM) for 3 h. At the end of treatment, the ROS formation was determined using the fluorescent probe DHE. (B) Representative bright field (BF) and DHE fluorescence images. Data are expressed as AUF and reported as mean ± SD of three independent experiments (^§§§ p < 0.001 vs. untreated cells, * p < 0.05 vs. cells treated with OAβ_1–42 at one-way ANOVA with Bonferroni post-hoc test). Scale bars: 100 µM.