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Detoxifying metabolism: Phase I and Phase II. CYP: cytochrome P450 monooxygenase, ARE genes: antioxidant-response elements; Nrf-2: nuclear factor erythroid 2 related factor 2; Keap-1: Kelch-like epichlorochydrin-associated protein 1; NADPH quinine oxidoreductase 1: NQO-1; glutathione S-transferase: GST; heme oxygenase 1: HMO-1; glutathione peroxidase: GPX.
