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. 2020 Jun 17;9(6):532. doi: 10.3390/antiox9060532

Figure 5.

Figure 5

Mechanisms of the carotenoids-mediated p53-induced apoptosis of cancer cells. Bcl-2: B-cell lymphoma 2; Bad: Bcl-2-associated agonist of cell death; Bak: Bcl-2 homologous antagonist/killer; Bax: Bcl-2-associated X protein; Bcl-xL: Bcl-extra-large; Bid: BH3 interacting-domain death agonist; Bim: Bcl-2-like protein 11; Noxa: Latin for damage, also known as phorbol-12-myristate-13-acetate-induced protein PMAIP1; PARP: poly (ADP-ribose) polymerase.