Table 1.
Metabolites’ concentrations (mmol/L), expressed as mean ± standard deviation, quantified by 1H-NMR in bronchoalveolar fluid (BALF) samples of control group (Group C) and asthma group (Group A). 95% CI for each group is indicated in brackets. P values are indicated for each metabolite, statistical significances (*) are in bold letters
| Metabolites | Group C (n = 6) | Group A (n = 6) | P values |
|---|---|---|---|
| Formate* | 1.17E-02 ± 1.77E-03 (1.02E-02 – 1.31E-02) | 1.21E-02 ± 5.01E-03 (8.05E-03 – 1.61E-02) | 0.040 |
| Lactate | 1.42E-02 ± 3.88E-03 (1.11E-02 – 1.73E-02) | 1.29E-02 ± 2.12E-03 (1.12E-02 – 1.46E-02) | 0.210 |
| Myo-inositol* | 2.82E-02 ± 1.70E-02 (1.46E-02 – 4.18E-02) | 1.58E-02 ± 5.88E-03 (1.11E-02 – 2.05E-02) | 0.036 |
| Glycerol* | 1.55E-03 ± 1.55E-03 (3.13E-04 – 2.80E-03) | 1.03E-03 ± 3.12E-04 (7.78E-04 – 1.28E-03) | 0.003 |
| Glycine | 5.48E-03 ± 1.43E-03 (4.33E-03 – 6.62E-03) | 4.46E-03 ± 1.44E-03 (3.31E-03 – 5.61E-03) | 0.994 |
| Taurine | 6.32E-03 ± 4.44E-03 (2.77E-03 – 9.88E-03) | 1.03E-02 ± 9.45E-03 (1.78E-03–2.73E-02) | 0.123 |
| Creatine | 1.60E-03 ± 8.37E-04 (2.27E-04–9.3E-03) | 1.55E-03 ± 6.60E-04 (1.02E-03 – 2.08E-03) | 0.615 |
| Succinate | 8.89E-04 ± 1.29E-04 (7.86E-04 – 9.92E-04) | 8.49E-04 ± 2.26E-04 (1.03E-04–6.69E-03) | 0.245 |
| Pyruvate | 9.46E-04 ± 2.96E-04 (7.09E-04 – 1.18E-03) | 7.57E-04 ± 2.70E-04 (5.41E-04 – 9.74E-04) | 0.845 |
| Acetate | 1.42E-02 ± 1.22E-03 (1.33E-02 – 1.52E-02) | 1.41E-02 ± 2.18E-03 (1.23E-02 – 1.58E-02) | 0.230 |
| Ethanol | 4.60E-03 ± 1.28E-03 (3.58E-03 – 5.62E-03) | 4.61E-03 ± 7.68E-04 (3.99E-03 – 5.22E-03) | 0.289 |
| Isopropanol* | 1.53E-03 ± 3.16E-04 (1.28E-03 – 1.79E-03) | 3.66E-03 ± 5.22E-03 (5.18E-04 – 7.84E-03) | < 0.001 |