Figure 9. Expected and observed likelihood of phagolysosomes to achieve pH of 4 or less.

(A) The expected proportions of murine BMDM phagolysosomes to achieve pH equal to or less than 4 assuming a normal distribution based on all observed data. (B) The expected proportions of human macrophage phagolysosomes to achieve pH equal to or less than 4 assuming a normal distribution based on the observed data. Expected proportions of macrophages to achieve pH equal to or less than 4 were calculated by assuming a normal distribution centered around a mean and standard deviation calculated from the observed data. (C) The observed proportions of murine BMDM phagolysosomes to achieve pH equal to or less than 4. (D) The observed proportions of human macrophage phagolysosomes to achieve pH equal to or less than 4.