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. 2020 Jun 5;8:386. doi: 10.3389/fcell.2020.00386

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Copyright © 2020 Konkova, Ershova, Savinova, Malinovskaya, Shmarina, Martynov, Veiko, Zakharova, Umriukhin, Kostyuk, Izhevskaya, Kutsev, Veiko and Kostyuk.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Transcription of satellite III in human cells. (A) Processing the nuclei with RNase A reduces the FISH-signal area. (1) Examples of the nuclei of SZ patients and nuclei of irradiated HC cells treated and untreated with RNase A before the FISH. (2) Cumulative histograms of the frequency distribution of the FISH signals by the square S^FISH for treated and untreated with RNase A intact HC, irradiated HC (50 cGy, 48 h), and SZ lymphocytes. (B) Transcription of f-SatIII DNA (HS3-1). (1) Irradiated lymphocytes (72 h after exposure). (2) White blood cells of SZ and HC groups. (C) Transcription of satellite III located on chromosome 9 (HS3-9). (1) Irradiated lymphocytes (72 h after exposure). (2,3) White blood cells of SZ and HC groups. (D) Dependence of the amount of RNA HS3-1 on the amount of RNA HS3-9 for two groups.