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. 2020 Jun 11;22(2):1507–1517. doi: 10.3892/mmr.2020.11223

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Copyright: © Zeng et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 7. — LIN28B expression is inhibited by propofol. (A) Expression of LIN28B in A2780 cells administered with different concentration of propofol was measured using Western blotting. (B) Expression of LIN28B in LIN28B knockdown A2780 cells was assessed by Western blotting. (C) Expression of LIN28B in A2780 cells administered with 10 µg/ml propofol at different times was evaluated using Western blotting. (D) Transwell migration and invasion assay of A2780 cells and LIN28B knockdown A2780 cells. Original magnification, ×400. (E) Viability of A2780 cells and A2780 knockdown cells was measured using MTT assay. (F) Proliferation of A2780 cells and A2780 knockdown cells determined by cell counts assay. Data are presented as the mean ± SD. **P<0.01, ***P<0.001 vs. control. miR, microRNA; LIN28B, lin-28 homolog B; sh, short hairpin RNA.