Table 1.
Baseline characteristics and laboratory results of CPUO patients and healthy subjects.
| Factors | Healthy subjects n = 20 |
CPUO patients n = 10 |
P value |
|---|---|---|---|
| Age, years | 50 (20-70) | 64 (47-80) | .041 |
| Male sex, n (%) | 9 (45.00) | 4 (40.00) | .999 |
| Hemoglobin, g/dL | 13.3 (11.7-15.3) | 12.1 (10.8-15.3) | .123 |
| White blood cell, cells/mm3 | 7180 (4350-10 550) | 6100 (4540-15 400) | .094 |
| PMN, % | 58.4 (41.4-77.1) | 52.2 (41.9-70.7) | .252 |
| Lymphocyte, % | 29.6 (17.6-46.3) | 34.1 (12.0-42.6) | .234 |
| Monocyte, % | 7.3 (4.4-11.6) | 7.1 (5.9-9.8) | .894 |
| Eosinophils, % | 4.5 (0-16.5) | 3.4 (0.4-10.1) | .270 |
| Blood urea nitrogen, mg/dL | 10.6 (7.0-19.1) | 14.7 (10.6-18.4) | .029 |
| Serum creatinine, mg/dL | 0.75 (0.48-1.31) | 0.84 (0.69-1.41) | .074 |
| Albumin, g/dL | 4.4 (2.7-4.7) | 4.5 (4.2-5.1) | .224 |
| Globulin, g/dL | 3.1 (2.5-4.0) | 3.1 (2.7-3.5) | .839 |
| Total bilirubin, mg/dL | 0.4 (0.1-1.3) | 0.5 (0.3-0.8) | .475 |
| ALT, U/L | 15.0 (9.0-26.0) | 23.0 (6.0-41.0) | .340 |
| AST, U/L | 20.0 (14.0-34.0) | 26.5 (13.0-54.0) | .548 |
| Alkaline phosphatase, U/L | 73.0 (41.0-120.0) | 74.0 (35.0-103.0) | .698 |
| Interleukin-31, pg/mL | 34.4 (20.4-56.8) | 127.3 (100.5-154.2) | <.001 |
Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; CPUO, chronic pruritus of unknown origin; PMN, polymorphonuclear leukocytes.
Data presented as median (range) unless indicated otherwise.