Table 4. Diagnostic performance of Tg, CT and CHFR1 for discriminating patients with PTC from PTC and MTC groups.

	Sensitivity % (95% CI)	Specificity % (95% CI)	Cut-off	AUC (95% CI)	P-value
MTC vs PTC
CT	21.62 [9.83–38.21]	98.07 [95.13–99.47]	7.74 pg/ml	0.60 [0.50–0.66]	0.7401
Tg	40.54 [24.75–57.90]	74.80 [66.17–82.19]	21.02 ng/ml	0.58 [0.50–0.65]	0.6459
CFHR1	100.00 [90.75–100.00]	85.08 [80.03–89.27]	0.92 ng/ml	0.93 [0.89–0.95]	<0.001
CFHR1+CT	21.62 [9.83–38.21]	98.90 [96.07–99.87]	–	0.91 [0.87–0.95]	<0.001
FTC vs PTC
CT	33.33 [4.33–77.72]	69.86 [63.14–75.99]	1.01 pg/ml	0.52 [0.45–0.58]	0.3446
Tg	100.00 [54.07–100.00]	30.08 [22.14–39.00]	5.71 ng/ml	0.65 [0.56–0.73]	0.1074
CFHR1	100.00 [54.07–100.00]	11.69 [7.97–16.36]	0.55 ng/ml	0.56 [0.50–0.62]	0.4496
CFHR1+CT	33.33 [4.33–77.72]	71.58 [64.46–77.99]	–	0.52 [0.45–0.60]	0.3661

Note:

CI, confidence interval.