Table 1.
Demographic and inflammatory parameters of the study cohort
| Non-IBD control | Anti-TNF | Corticoid | p-value | |
|---|---|---|---|---|
| Donors | 31 | 31 | 16 | |
| Sex [F/M] | 24/7 | 20/11 | 12/4 | |
| Age [years] [range] | 35 [19–65] | 38 [19–58] | 39 [20–65] | |
| CDAI | N/A | 14–1088 | 37–549 | |
| Calprotectin [µg/g] | 105.10 ± 15.87 | 685.21 ± 111.81 | 707.03 ± 158.66 | <0.0001**** |
| sCD14 [ng/mL] | 1353.26 ± 85.73 | 1155.66 ± 129.31 | 1158.60 ± 147.90 |
IBD, inflammatory bowel disease; TNF, tumour necrosis factor; CDAI, Crohn’s Disease Activity Index. The analyses used to test for statistically significant differences are described in the Methods section. A p-value less than 0.05 was considered statistically significant; p-values ≥0.05 are not shown. ****ANOVA with multiple comparisons was used to determine statistical significance for calprotectin levels, p < 0.0001.