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Diagnostic criteria for tuberous sclerosis complex[5]
| Major Criteria | Minor Criteria |
|---|---|
| Hypomelanotic macule ≥3 | Confetti skin lesions |
| Angiofibromas ≥3 | Dental enamel pits (>3) |
| Ungual fibroma ≥2 | Intraoral fibroma (≥2) |
| Shagreen patch | Retinal achromic patch |
| Multiple renal hamartomas | Multiple renal cysts |
| Cortical dysplasia | Non-renal hamartoma |
| Subependymal nodules | |
| Subependymal giant cell astrocytoma | |
| Cardiac rhabdomyoma | |
| Lymphangioleiomyomatosis | |
| Angiomyolipoma | |
| Hypomelanotic macule |
