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. 2020 Jul;36:1–9. doi: 10.1016/j.euroneuro.2020.03.024

Table 3.

Within-individual hazard ratios of violent crime over period after treatment initiation and discontinuation.

Reference
Before ever-treatment
From treatment initiation
From treatment discontinuation
0–28 days 29–84 days >84 days 0–28 days 29–84 days >84 days
Overall No. events 13,229 847 1483 3976 922 1400 10,346
HR (95% CI)a 1.00 1.28 (1.13, 1.45) 1.35 (1.22, 1.49) 1.24 (1.14, 1.35) 1.37 (1.21, 1.55) 1.20 (1.08, 1.33) 0.94 (0.88, 1.01)
15–24 No. events 6825 330 538 1104 315 470 2970
HR (95% CI)a 1.00 1.25 (1.02, 1.53) 1.37 (1.16, 1.62) 1.13 (0.98, 1.30) 1.42 (1.16, 1.74) 1.01 (0.85, 1.19) 0.86 (0.76, 0.96)
25–34 No. events 2715 201 368 978 204 363 2973
HR (95% CI)a 1.00 1.35 (1.02, 1.80) 1.55 (1.23, 1.95) 1.47 (1.21, 1.79) 1.37 (1.02, 1.82) 1.42 (1.13, 1.79) 1.03 (0.87, 1.22)
35–44 No. events 2147 164 307 960 209 312 2286
HR (95% CI)a 1.00 1.02 (0.74, 1.40) 1.18 (0.91, 1.53) 1.11 (0.89, 1.39) 1.26 (0.92, 1.72) 1.03 (0.80, 1.32) 0.90 (0.74, 1.09)
45–60 No. events 1542 152 270 934 194 255 2117
HR (95% CI)a 1.00 1.29 (0.91, 1.82) 1.08 (0.82, 1.43) 1.26 (1.00, 1.58) 1.15 (0.82, 1.55) 1.15 (0.87, 1.53) 0.87 (0.71, 1.08)
a

Adjusted for time-varying covariates: age, recent violent crime, use of non-SSRI antidepressants, benzodiazepines, and other psychotropic medications.