Fig. 6.

MBD3/NuRD deficiency elicits a different response in human and mouse primed pluripotent stem cells. A) Schematic of the analysis: the Venn diagram shows the overlap of differentially expressed genes identified in human cells, and the identified human orthologues of those identified in mEpiSCs. K-means clustering of this set of 153 genes in human data led to the formation of three gene clusters and to four gene clusters in mouse data. B). Expression profiles are shown for the different gene clusters. Error bars indicate standard deviations of average expression. Expression profiles of human and mouse gene clusters with similar expression patterns in wild type cells are displayed together, and the number of common genes is shown. GO terms are available in Table S9.