Table 1.

Rome IV Diagnostic Criteria for Cyclical Vomiting Syndrome and Cannabinoid Hyperemesis Syndrome⁴¹

Cyclical vomiting syndrome (CVS)	Cannabinoid hyperemesis syndrome (CHS)
Acute onset of stereotypical vomiting episode that lasts less than 1 week	Stereotypical vomiting episodes similar to CVS
At least three episodes in the previous year, two episodes in the last 6 months at least 1 week apart	Presentation following sustained excessive cannabis use
No vomiting between episodes	Relief from vomiting after abstinence from cannabis
Symptoms must be present for 3 months with onset 6 months earlier	Symptoms must be present for 3 months with onset 6 months earlier
Supportive criteria: history of migraine headaches	Supportive criteria: pathological bathing behavior (prolonged hot baths or showers)