Table 1. Demographic and clinical characteristics of assessed patients.
| Baseline Clinical Characteristics | Assessed Patients N: 147 | Without MAS N: 121 | MAS N: 26 |
|---|---|---|---|
| Age, Mean±SD | 45.2±16.1 | 44.5±15.6 | 48.46±18.4 |
| Female, N (%) | 58 (39.5%) | 50 (41.3%) | 8 (30.7%) |
| Clinical Features | |||
| Fever, N (%) | 147 (100%) | 121 (100%) | 26 (100%) |
| Arthritis, N (%) | 130 (88.4%) | 108 (89.2%) | 22 (84.6%) |
| Skin Rash, N (%) | 110 (74.8%) | 91 (75.2%) | 19 (73.1%) |
| Splenomegaly, N (%) | 98 (66.7%) | 77 (63.6%) | 21 (80.8%) |
| Myalgia, N (%) | 95 (64.6%) | 73(60.3%) | 22 (84.6%) |
| Liver involvement, N (%) | 91 (61.9%) | 70 (57.8%) | 21 (80.8%) |
| Sore throat, N (%) | 83 (56.5%) | 62 (51.2%) | 21 (80.8%) |
| Lymph node, N (%) | 80 (54.4%) | 59 (48.8%) | 21 (80.8%) |
| Pericarditis, N (%) | 31 (21.1%) | 21 (17.4%) | 10 (38.5%) |
| Pleuritis, N (%) | 29 (19.7) | 20 (16.5%) | 9 (34.6%) |
| Abdominal pain, N (%) | 20 (13.6%) | 13(10.7%) | 7 (27.0%) |
| AOSD pneumonia, N (%) | 18 (12.2%) | 14 (11.6%) | 4 (15.4%) |
| Systemic score, Mean±SD | 6.0±2.0 | 5.7±1.9 | 7.6±1.9 |
| Laboratory Parameters | |||
| Leucocytosis >15000mm3, N (%) | 78 (53.1%) | 63 (52.1%) | 15 (46.1%) |
| Ferritin ng/ml, median (IQR) | 1271.0 (2484.0) | 1120.0 (28000.0) | 2746.7 (17136.8) |
| ESR mm/Hr, Mean±SD | 69.4±27.3 | 67.8±27.1 | 76.3±27.8 |
| CRP mg/L, median (IQR) | 50.0 (101.0) | 50.0 (348.0) | 56.5 (204.0) |
| Therapy | |||
| CCSs, N (%) | 147 (100%) | 66 (54.6%) | 20 (76.9%) |
| Low dosage CCSs, N (%) | 61 (41.5%) | 55 (45.4%) | 6 (26.1%) |
| sDMARDs, N (%) | 95 (64.5%) | 75 (62.0%) | 20 (77.0%) |
| bDMARDs, N (%) | 44 (29.9%) | 37 (30.6%) | 7 (27.0%) |
| Disease course | |||
| Monociclic pattern, N (%) | 53 (36.1%) | 49 (40.5%) | 4 (15.4%) |
| Polyciclic pattern, N (%) | 48 (32.7%) | 44 (36.4%) | 4 (15.4%) |
| Chronic pattern, N (%) | 38 (25.9%) | 29 (24.0%) | 9 (34.6%) |
| Mortality, N (%) | 20 (13.6%) | 9 (7.4%) | 11 (42.3%) |
| Follow up, median (IQR) years | 2 (16.4) | 2.5 (14.4) | 1 (16.4) |
AOSD = Adult Onset Still’s Disease; CCSs = Corticosteroids; ESR = Erythrocyte Sedimentation Rate; CRP = C Reactive Protein; sDMARDs = synthetic Disease Modifying Anti-Rheumatic Drugs; bDMARDs = biologic Disease Modifying Anti-Rheumatic Drugs; N = Number