Table 1. Sleep parameters measured by polysomnography comparing the three HOMER1 rs3822568 SNP genotypes.

Polysomnographic parameter	rs3822568 genotype	N	Mean (SD)	F(2,980)	p
Sleep latency (minutes)	AA	219	17.14 (21.82)	6.389	0.002
	AG	469	14.57 (16.23)
	GG	295	20.48 (29.74) *
REM sleep latency (minutes)	AA	219	98.71 (54.99)	0.596	0.551
	AG	469	102.03 (54.15)
	GG	295	98.01 (52.22)
Sleep total time (minutes)	AA	219	346.19 (85.67)	2.962	0.052
	AG	469	347.28 (71.43)
	GG	295	333.82 (80.64)
Sleep efficiency (%)	AA	219	81.18 (13.9)	3.433	0.033
	AG	469	82.94 (11.71)
	GG	295	80.56 (13.95) *
Stage 1 (%)	AA	219	4.86 (3.72)	1.725	0.179
	AG	469	4.68 (3.28)
	GG	295	4.33 (3.19)
Stage 2 (%)	AA	219	54.87 (8.75)	0.284	0.753
	AG	469	54.67 (9.57)
	GG	295	54.28 (9.23)
Stages N3 (%)	AA	219	21.23 (7.35)	3.276	0.038
	AG	469	21.53 (8.23)
	GG	295	22.85 (8.29)
REM sleep (%)	AA	219	19.04 (6.72)	0.771	0.463
	AG	469	19.13 (6.48)
	GG	295	18.54 (6.47)
Awake time (minutes)	AA	219	62.72 (50.2)	0.868	0.420
	AG	469	57.83 (44.73)
	GG	295	59.74 (43.19)
Number of arousals per hour	AA	219	16.61 (11.6)	6.075	0.002
	AG	469	15.16 (11.69)
	GG	295	13.27 (9.12) *
Apnea-hypopnea index	AA	219	9.89 (14.98)	3.988	0.019
	AG	469	8.33 (13.18)
	GG	295	6.63 (11.13) *

One-way ANOVA on z-score standardized measurements; SD: standard deviation; REM: rapid eye-movement.

* Indicates p<0.05 when compared to the other genotypes inside each variable.