Fig 3. Prolonged administration of isoproterenol causes similar histopathologic changes in hearts of male and female mice.
Male and female C57Bl/6NCrl mice were subcutaneously injected with 10 mg/kg isoproterenol (ISO) (male, female n = 6, 5, respectively) or saline (male, female n = 5) daily for 14 days. Fig 3 shows representative images from hematoxylin and eosin (HE), Masson’s trichrome, and MAC-2 stained sections.