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. 2020 Jul 9;15(7):e0234993. doi: 10.1371/journal.pone.0234993

Table 1. Select inflammatory and immune response genes.

Gene Symbol Log2 Fold Change p-value (adjusted) Function (Uniprot ID)
Interferon Related OASL 1.923812 7.63E-18 Type I/II interferon signaling pathway–RNA binding (Q15646)
IFITM1 1.336366 1.99E-13 Type I/II interferon signaling pathway–Inhibits entry of virus (P13164)
IFIT3 1.228324 6.81E-11 Type I/II interferon signaling pathway–Inhibits viral processes (O14879)
IFIT1 1.4001 1.51E-10 Type I interferon signaling pathway–RNA binding (P09914)
RSAD2 1.424712 7.87E-09 Type I interferon signaling pathway–CD4+ T-cell activation (Q8WXG1)
OAS2 1.064886 3.93E-06 Type I/II interferon signaling pathway–Innate antiviral response (P29728)
OAS1 1.061772 1.35E-05 Type I/II interferon signaling pathway–Innate antiviral response (P00973)
IFITM3 0.677765 2.45E-05 Type I/II interferon signaling pathway–Inhibits entry of virus (Q01628)
IFI27 0.865445 0.000102 Type I interferon signaling pathway–Innate immune response (P40305)
IFITM2 0.57169 0.000815 Type I/II interferon signaling pathway–Inhibits entry of virus (Q01629)
IRF7 0.764681 0.004436 Type I/II interferon signaling pathway–Key transcriptional regulator (Q92985)
OAS3 0.72591 0.008201 Type I/II interferon signaling pathway–Innate antiviral response (Q9Y6K5)
IFI35 0.759788 0.012529 Type I interferon signaling pathway (P80217)
GBP2 0.400131 0.049661 Type I/II interferon signaling pathway–anti-pathogen activity (P32456)
STAT1 0.734634 1.89E-05 Signal transducer–Mediates interferon response (P42224)
STAT2 0.45657 0.026725 Signal transducer–Mediates interferon response (P52630)
Chemokine/cytokine Related CCL5 1.355304 4.67E-09 Chemotaxis–Monocytes, T-helper cells, eosinophils, neutrophils (P13501)
CXCL2 0.927644 3.00E-07 Chemotaxis–Leukocytes, neutrophils (P19875)
CXCL1 0.734937 1.35E-05 Chemotaxis–Neutrophils (P09341)
CXCL6 0.654966 2.30E-05 Chemotaxis–Neutrophils, leukocytes (P80162)
CCL2 0.479371 0.002206 Chemotaxis–Monocytes, basophils (P13500)
CXCL3 0.837774 0.005424 Chemotaxis–Leukocytes, neutrophils (P19876)
ELANE 0.819051 0.007334 Modulates natural killer cells, monocytes, granulocytes, neutrophils (P08246)
CXCL5 0.652521 0.009551 Chemotaxis–Neutrophils, leukocytes (P42830)
CCR7 0.659729 0.009835 Chemokine receptor–mediates immune cell chemotaxis (P32248)
CCL13 0.714727 0.032672 Chemotaxis–Monocytes, lymphocytes, basophils, eosinophils (Q99616)
C3 0.68928 0.037701 Complement system (P01024)