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. 2020 Jul 9;15(7):e0234993. doi: 10.1371/journal.pone.0234993

Table 2. Select genes involved in cell-cell junctions, tight junctions, and adherens junctions.

Gene Symbol Log2 Fold Change p-value (adjusted) Function (Uniprot ID)
Functional component CLDN14 -0.77849 0.014354 Tight junction protein; Cell adhesion (O95500)
PCDH10 -0.70536 0.000243 Protocadherin; cell-cell adhesion (Q9P2E7)
CDH2 -0.65003 3.70E-07 Adherens junction protein; Cell adhesion (P19022)
MAGI1 -0.42719 0.03935 Scaffolding/Tight Junction Protein; Cell adhesion (Q96QZ7)
PCDH7 -0.39693 0.011885 Protocadherin; cell-cell adhesion (O60245)
Regulatory component PODXL -0.97617 6.91E-07 Positive/negative regulation of cell adhesion (O00592)
TWF1 -0.67896 0.038453 Actin binding; Cadherin binding; Focal adhesion (Q12792)
NEXN -0.63395 0.015809 Actin binding protein; Cell adhesion (Q0ZGT2)
MTSS1 -0.53155 0.000231 Actin binding protein; Positive regulation of cell-cell junctions, adhesion (O43312)
FLT1 -0.50364 0.01255 VEGF receptor; Endothelial proliferation, survival, cell adhesion (P17948)
ATP1B1 -0.47766 0.034878 ATPase non-catalytic beta subunit; Cell adhesion; Epithelial cell polarity (PO5026)
MYLK -0.43527 0.014211 Regulates tight junctions; Regulates epithelial cell survival, wound healing (Q15746)
CCND1 -0.37679 0.008102 Regulates cell cycle; Interactions with tight junction proteins (P24385)
FRMD4A -0.3571 0.017093 Scaffolding Protein–Regulates epithelial cell polarity, adherens junctions (Q9P2Q2)
CAPN2 -0.33762 0.047708 Protease; Negative regulation of junction and adhesive pathways (P17655)
PALLD -0.30542 0.041217 Scaffolding/Cytoskeletal protein; Cell adhesion (Q8WX93)