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. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: J Physiol. 2020 May 21;598(13):2589–2605. doi: 10.1113/JP278503

Table 2.

Resting upright metabolic and hemodynamic variables

Middle-age untrained Older untrained Older trained ANOVA p value
V̇O2, ml.kg−1.min−1 3.1 (2.8 - 3.5) (21) 3.0 (2.9 - 3.3) 3.3 (2.8 - 3.7) 0.420
V̇O2, ml.kgFFM−1.min−1 4.9 (4.5 - 5.0) (20) 4.8 (4.5 - 5.4) 4.6 (4.0 - 5.5) (12) 0.663
Q̇, L.min−1 3.3 (2.9 - 3.7) 3.1 (2.8 - 3.4) 3.4 (3.0 - 3.8) 0.169
QI, L.m2.min−1 1.90 (1.68 - 2.13) 1.80 (1.60 - 1.95) 2.20 (1.95 - 2.45) <0.001
Q̇, ml.kgFFM−1.min−2 84.3 (67.4 - 88.7) (21) 76.0 (70.0 - 83.0) 86.5 (77.3 - 91.8) (12) 0.048
CPO, watts 0.68 (0.59 - 0.74) (20) 0.60 (0.50 - 0.70) 0.70 (0.60 - 0.80) 0.111
Heart rate, b.min−1 86.8 ± 12.7 85.8 ± 10.1 72.2 ± 7.1* <0.001
SV, ml 37.8 (33.6 - 43.3) 36.2 (31.6 - 41.8) 46.1 (39.6 - 59.9)* 0.006
SV, ml.m2 22.0 (19.9 - 25.0) 21.0 (18.4 - 24.2) 30.1 (25.7 - 38.2)* <0.001
SV, ml.kgFFM−1 0.96 ± 0.18 0.90 ± 0.18 1.18 ± 0.18* (12) <0.001
MAP, mmHg 89.8 (86.4 - 99.7) (20) 89.0 (84.3 - 101.0) 93.7 (90.6 - 99.7) 0.406
Ea, mmHg.ml−1.m2 4.7 ± 1.1 (20) 5.2 ± 1.1 3.8 ± 0.7 <0.001
SAC, ml.mmHg−1.m2 0.8 (0.6 - 1.0) (20) 0.6 (0.4 - 0.7)* 0.7 (0.6 - 0.9) 0.006
SVR, dynes.s−1.cm−5 2243.2 (1964.7 - 2769.6) (20) 2353.4 (2054.6 - 2774.0) 2161.5 (2049.6 - 2592.4) 0.605
a-vDO2, ml.100 ml−1 6.1 ± 1.0 6.7 ± 1.2 5.5 ± 0.9 0.003

Parametric and nonparametric sampling distributions are shown as mean ± SD or median (25% - 75%) respectively. Parametric data was analysed by 1-way ANOVA with post hoc analysis (Bonferroni t-tests method) and nonparametric data by Kruskal–Wallis ANOVA on Ranks with post hoc analysis (Dunn’s method). The single number in parentheses represents the number of observations if different from the stated n in Table 1.

V̇O2, oxygen uptake; Q̇, cardiac output; CPO, cardiac power; SV, stroke volume; MAP, mean arterial pressure; Ea, effective arterial elastance; SAC, systemic arterial compliance; SVR, systemic vascular resistance; a-vDO2, arterial-venous oxygen content difference

*

p <0.05 older trained versus middle-age untrained

p <0.05 older trained versus older untrained