Table 2:
Clinical Characteristics by Beta-Receptor Function in HFpEF
| Blunted | Preserved | p value | |
|---|---|---|---|
| Subjects, n | 6 | 7 | |
| Sinus β-receptor sensitivity (bpm/(ngISO/kg/min)) | 0.050 ± 0.050 | 0.247 ± 0.111 | |
| Age (years) | 68 ± 6 | 67 ± 6 | 0.77 |
| Women, n (%) | 3 (50%) | 4 (57%) | 0.59 |
| Diabetes mellitus, n (%) | 4 (67%) | 3 (43%) | 0.43 |
| Norepinephrine Baseline | 488 ± 232 | 359 ± 214 | 0.32 |
| Peak Heart Rate (bpm) | 111 ± 16 | 122 ± 14 | 0.20 |
| % Predicted heart rate | 75 ± 13 | 80 ± 8 | 0.41 |
| Peak VO2 (ml/min/kg) | 13.7 ± 2.4 | 13.3 ± 2.3 | 0.77 |
| Peak Stroke Volume (ml) | 100 ± 18 | 94 ± 19 | 0.59 |
| Peak AVO2 difference (%) | 11.6 ± 2.8 | 11.8 ± 1.4 | 0.87 |
| Peak RER | 1.06 ± 0.08 | 1.01 ± 0.11 | 0.34 |
| Peak lactate (mmol/L) | 3.4 ± 1.1 | 3.7 ± 2.0 | 0.75 |
Group characteristics in HFpEF subjects with blunted or preserved sinus node function.