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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: Allergy. 2020 Jan 31;75(9):2254–2266. doi: 10.1111/all.14181

Figure 3: Decreased Th2 airway responses in ST2 deficient mice exposed to HDM and DEP.

Figure 3:

(A) Airway resistance was measured a day after the last challenge (n=4–7 mice/group; 1 or 2-way ANOVA, *** p<0.001) (B) Proportions of BALF eosinophil and neutrophils (n=4–7 mice/group). (C) Total BALF eosinophil and T-cell counts compiled from 3 separate experiments (n=11–22 mice/group). (D) Representative photomicrograghs of PAS-stained large airway sections. (E) BALF IL5 and IL13 levels were assessed by ELISA (n=7–15 mice/group from 2 separate experiments). (F) IL13 lung mRNA levels were assessed by real time PCR and expressed as ratio over Hprt (n=4–7 mice/group). Statistical significance was assessed by t-test (p=value) or 1-way ANOVA; *p<0.05, ** p<0.01, *** p<0.001, n.s.= not significant).