TABLE 2.
Relationship between enteral nutrition type (breast milk versus formula) and brain volume
| Brain volume (cm3) Mean (95% CI) | Breast milk (n = 43) | Formula (n = 24) | Pa |
|---|---|---|---|
| Total brain volume | 322 (312-331) | 305 (293-318) | .04 |
| Cortical grey matter | 126 (122-129) | 119 (114-124) | .06 |
| White matter | 142 (137-147) | 137 (130-143) | .20 |
| Deep grey matter | 24 (24-25) | 23 (22-24) | .05 |
| Amygdala-hippocampus | 2.3 (2.3-2.4) | 2.1 (2.0-2.2) | <.01 |
| Cerebellum | 22 (21-23) | 19 (18-20) | <.01 |
| Brainstem | 5.3 (5.2-5.4) | 5.0 (4.8-5.2) | .02 |
a
Based on least squares means estimates from generalised linear models adjusted for gestational age at birth, postmenstrual age at MRI and average weight gain.