Table 2.
Summary of differentially expressed genes related to cell apoptosis and the cell cycle determined by RNA-Seq analysis.
| KEGG enrichment | Type of genes/regulators | Genes | Gene change |
|---|---|---|---|
| Ribosome | 60S ribosomal protein | RPL10A, RPL14, RPL17, RP L22, RPL23 | up |
| 40S ribosomal protein | PPS18, RPS3A, RPS26, RPS27A | up | |
| mitochondrial ribosomal protein | MRPL12, MRPS14, MRPL1, MRPL27 | up | |
| Oxidative phosphorylation | ATP synthase | ATP5PO, ATP6V1G1, ATP5F1C | up |
| NADH dehydrogenase | NDUFA8, NDUFS4, NDUFB2, NDUFB6 | up | |
| cytochrome C oxidase | COX5B, UQCRC2 | up | |
| PI3K/Akt signaling pathway | up-regulator | EPHA2, ITGB4, EFNA1, IL2RG, TNC, CSF3,MYC | down |
| down-regulator | PTEN | up | |
| mTOR signaling pathway | up-regulator | ATP6V1G1, FZD2, LAMTOR2 | up |
| SLC3A2, SLC7A5, ITGA9, LRP5 | down | ||
| down-regulator | PTEN | up |