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. 2020 Apr 18;69(8):1577–1588. doi: 10.1007/s00262-020-02571-2

Table 3.

Results of cox regression (multivariate analysis) on late-stage cohort

Parameter HR CI p value
Differentiation moderate 2.3 1.2–4.5 0.012
Differentiation poor 4.5 2–10.4 0.0001
Carcinoma size (cm) 1.14 1.01–1.3 0.031
T stage 4 2 1.13–3.5 0.017
Node stage 1 (0–2) 0.32
Node stage 2 (0–2) 0.073
Node stage 1b 0.437
Node stage 2a 0.077
Node stage 2b 0.584
HLA (normal epithelium) 0.664
HLA (normal stroma) 0.277
HLA (carcinoma epithelium) 0.99
HLA (carcinoma stroma) 0.89
No. of nodes 0.584

Bolded p values < 0.05 were deemed statistically significant

–Indicates no HR or CI reported during statistical analysis when p > 0.05

HR hazard ratio, CI confidence interval