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. 2020 Jul 9;10:11358. doi: 10.1038/s41598-020-68255-0

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Molecular degree of perturbation is independent of biological sex in patients with active tuberculosis. (A) Perturbed probability according to the age. Spearman correlation rank was compared used Steger Method. (B) Spearman correlation analysis was used to test association between age and MDP values of each biomarker in either male or female TB patients. Bars represent the Spearman rank (rho) values. Colored bars indicate statistically significant correlation (P < 0.05) after adjustment for multiple measurement.