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. 2020 Jul 9;5:57. doi: 10.1038/s41541-020-0206-5

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a Five days after pH1N1 challenge, mice were sacrificed, and the lung sections were stained with hematoxylin and eosin. Arrows indicated the perivascular and interstitial infiltration of inflammatory cells and the lung consolidation. b Pathological scores of the lungs 5 days after challenge. c The viral titer in the lung tissues was determined by quantitative PCR. d Lung virus titer was determined by the TCID50 assay. Five mice in each group. ***p < 0.01. ns no significance (determined using one-way ANOVA).