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. 2020 Jul 9;10:11349. doi: 10.1038/s41598-020-68269-8

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The effect of TRPV4 deletion on different phases of the cell cycle in esophageal keratinocytes. The percentages of cells in the G0/G1 (gray bars), S (orange bars) and G2/M phase (blue bars) in WT and TRPV-KO (V4KO) cultures at 0, 24, 48 and 72 h after insert removal. Data are presented as means ± SEM (n = 6–9). *p < 0.05 compared with the respective phase in WT cultures as determined by t-test.