Table 1.
Macaque experimental protocol.
| Group | Experiment | Macaque | MHC-I haplotype | SIVmac239 iva |
ARTb | SeV-Gag/Vif inc |
a-SIV IgG ivd |
|---|---|---|---|---|---|---|---|
| N | Exp 1 | NE1 | E | Wk 0 | Wk 12–32 | (−) | (−) |
| N | Exp 1 | NE2 | E | Wk 0 | Wk 12–32 | (−) | (−) |
| N | Exp 2 | NE3 | E | Wk 0 | Wk 12–32 | (−) | Wk 32 |
| N | Exp 1 | NW4 | W | Wk 0 | Wk 12–32 | (−) | (−) |
| N | Exp 2 | NW5 | W | Wk 0 | Wk 12–32 | (−) | Wk 32 |
| N | Exp 1 | NS6 | S | Wk 0 | Wk 12–32 | (−) | (−) |
| V | Exp 1 | VE1 | E | Wk 0 | Wk 12–32 | Wks 26 and 32 | Wk 32 |
| V | Exp 1 | VE2 | E | Wk 0 | Wk 12–32 | Wks 26 and 32 | Wk 32 |
| V | Exp 2 | VE3 | E | Wk 0 | Wk 12–32 | Wks 26 and 32 | Wk 32 |
| V | Exp 1 | VW4 | W | Wk 0 | Wk 12–32 | Wks 26 and 32 | Wk 32 |
| V | Exp 2 | VW5 | W | Wk 0 | Wk 12–32 | Wks 26 and 32 | Wk 32 |
| V | Exp 1 | VS6 | S | Wk 0 | Wk 12–32 | Wks 26 and 32 | Wk 32 |
aAnimals were intravenously inoculated with SIVmac239.
bAnimals received ART from week 12 to 32 post-infection.
cAnimals were intranasally immunized with SeV-Gag and SeV-Vif.
dAnimals were intravenously administered with anti-SIV IgG.