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. 2020 Jul 9;10:11374. doi: 10.1038/s41598-020-68186-w

Table 2.

Comparison of risks of long-term sequelae between the SNJ cases and reference cohort.

Different categories Reference cohort (n = 12,579) SNJ 2000–2003 follow-up cohort (n = 66,983)
n (%) n (%) OR aORa
Developmental delay 614 (4.9) 6,630 (9.9) 2.14* 1.63***
Infantile cerebral palsy 63 (0.5) 1,009 (1.5) 3.03* 1.35*
Lack of expected normal physiological development in childhood 218 (1.73) 2,277 (3.4) 1.99* 1.5***
Hearing loss 169 (1.3) 2,047 (3.1) 2.31* 1.74***
Developmental speech disorders 250 (2.0) 2,587 (3.9) 1.98* 1.51***
Dysarthria 178 (1.4) 1,553 (2.3) 1.65* 1.46***
Mental retardation 118 (0.9) 1,169 (1.8) 1.87* 1.27*
ADHD 324 (2.58) 2,523 (3.8) 1.48* 1.3***
Autism 61 (0.5) 593 (0.9) 1.83* 1.69***

SNJ significant neonatal jaundice, ADHD attention deficit hyperactivity disorder.

*P 0.05; **P 0.01; ***P 0.001.

aAdjusted for gender, urbanization levels and comorbid perinatal conditions (prematurity, hemolytic disease of newborn, and congenital or chromosome anomalies).