Table 2.
Comparison of risks of long-term sequelae between the SNJ cases and reference cohort.
| Different categories | Reference cohort (n = 12,579) | SNJ 2000–2003 follow-up cohort (n = 66,983) | ||
|---|---|---|---|---|
| n (%) | n (%) | OR | aORa | |
| Developmental delay | 614 (4.9) | 6,630 (9.9) | 2.14* | 1.63*** |
| Infantile cerebral palsy | 63 (0.5) | 1,009 (1.5) | 3.03* | 1.35* |
| Lack of expected normal physiological development in childhood | 218 (1.73) | 2,277 (3.4) | 1.99* | 1.5*** |
| Hearing loss | 169 (1.3) | 2,047 (3.1) | 2.31* | 1.74*** |
| Developmental speech disorders | 250 (2.0) | 2,587 (3.9) | 1.98* | 1.51*** |
| Dysarthria | 178 (1.4) | 1,553 (2.3) | 1.65* | 1.46*** |
| Mental retardation | 118 (0.9) | 1,169 (1.8) | 1.87* | 1.27* |
| ADHD | 324 (2.58) | 2,523 (3.8) | 1.48* | 1.3*** |
| Autism | 61 (0.5) | 593 (0.9) | 1.83* | 1.69*** |
SNJ significant neonatal jaundice, ADHD attention deficit hyperactivity disorder.
*P 0.05; **P 0.01; ***P 0.001.
aAdjusted for gender, urbanization levels and comorbid perinatal conditions (prematurity, hemolytic disease of newborn, and congenital or chromosome anomalies).