Table 4.
Relationship between serum 25(OH)D concentrations and prevalence of asthma, emphysema, and chronic bronchitis in US adults: National Health and Nutrition Examination Surveys 2007–2012 [odds ratio (95% confidence intervals)].
| Serum 25(OH)D quartiles | P-value | ||||
|---|---|---|---|---|---|
| Q1 | Q2 | Q3 | Q4 | ||
| Asthma | |||||
|
n Cases |
2,994 446 |
2,994 399 |
2,991 385 |
2,993 403 |
|
| Prevalence, % | 16.0 | 14.6 | 13.2 | 13.4 | 0.18 |
| Unadjusted OR (95% CI) | 1.23 (0.98–1.55) | 1.10 (0.86–1.42) | 0.98 (0.79–1.22) | 1.0 | 0.09 |
| Multivariable-adjusted OR (95% CI) | 1.19 (0.95–1.51) | 1.13 (0.87–1.46) | 1.01 (0.80–1.28) | 1.0 | 0.14 |
| Emphysema | |||||
|
n Cases |
2,993 39 |
2,993 29 |
2,991 34 |
2,995 54 |
|
| Prevalence, % | 1.7 | 0.9 | 1.3 | 1.4 | 0.19 |
| Unadjusted OR (95% CI) | 1.19 (0.76–1.88) | 0.62 (0.36–1.06) | 0.95 (0.58–1.54) | 1.0 | 0.99 |
| Multivariable-adjusted OR (95% CI) | 1.11 (0.66–1.87) | 0.69 (0.36–1.31) | 0.60 (0.36–0.99) | 1.0 | 0.89 |
| Chronic bronchitis | |||||
| N | 2,993 | 2,991 | 2,989 | 2,990 | |
| Cases | 147 | 115 | 142 | 176 | |
| Prevalence, % | 5.4 | 4.5 | 4.9 | 5.4 | 0.58 |
| Unadjusted OR (95% CI) | 0.99 (0.71–1.37) | 0.82 (0.57–1.17) | 0.89 (0.61–1.31) | 1.0 | 0.67 |
| Multivariable-adjusted OR (95% CI) | 1.06 (0.71–1.57) | 0.98 (0.64–1.49) | 0.95 (0.65–1.39) | 1.0 | 0.84 |