Table 1.
Multivariate logistic regression model for biomarkers showing associations with either radiographic and/or clinical features of OA.
| Outcome | sColl2-1 NO2 | sCS846 | sCOMP | uCTXII | ||||
|---|---|---|---|---|---|---|---|---|
| OR (95%) | p-value | OR (95%) | p-value | OR (95%) | p-value | OR (95%) | p-value | |
| KL grade | 1.1316 (1.0289, 1.2445) | 0.011 | 0.9972 (0.9913, 1.0032) | 0.364 | 0.9988 (0.9977, 0.9999) | 0.036 | 1.0607 (1.0231, 1.0996) | 0.001 |
| WOMAC pain | 1.0012 (0.9614, 1.0427) | 0.954 | 1.0032 (0.9999, 1.0065) | 0.056 | 0.9991 (0.9984, 0.9997) | 0.005 | 1.0138 (1.0023, 1.0253) | 0.018 |
| WOMAC Stiffness | 1.0137 (0.9710, 1.0584) | 0.535 | 1.0048 (1.0011, 1.0085) | 0.011 | 1.0005 (0.9999, 1.0012) | 0.110 | 1.0072 (0.9954, 1.0192) | 0.232 |
| JSN medial | 0.9967 (0.9511, 1.0446) | 0.892 | 1.0014 (0.9976, 1.0053) | 0.466 | 1.0002 (0.9994, 1.001) | 0.699 | 1.0164 (1.0013, 1.0318) | 0.033 |
| JSN lateral | 1.0704 (0.9967, 1.1495) | 0.062 | 0.9909 (0.9829, 0.9989) | 0.026 | 1.0015 (1.0004, 1.0027) | 0.008 | 0.9918 (0.9692, 1.015) | 0.484 |
| Osteophytes medial | 0.9860 (0.9168, 1.0605) | 0.705 | 0.9957 (0.9906, 1.0007) | 0.092 | 0.9998 (0.9986, 1.001) | 0.699 | 1.023 (0.9965, 1.0502) | 0.090 |
| Osteophytes lateral | 1.0561 (1.0059, 1.1089) | 0.028 | 1.0007 (0.9971, 1.0042) | 0.716 | 0.9997 (0.999, 1.0004) | 0.431 | 1.0205 (1.0061, 1.0351) | 0.005 |
Age, BMI, gender, and race were adjusted for in the model.
Statistically significant data are shown in bold.