Table 3.
Lifetime health outcomes
| Clinical outcome | No screening | ECG 12-lead | Z14 |
|---|---|---|---|
| Screening related outcomes | |||
| Number of AF detections | 779 | 833 | 1034 |
| Screening yield | 0 | 0.72% | 3.44% |
| Percentage of AF cases detected | 0 | 1.86% | 8.93% |
| Thromboembolic events | |||
| Ischemic stroke | 1105.34 | 1095.54 | 1063.11 |
| Myocardial infarction | 260.88 | 259.64 | 254.48 |
| Systemic embolism | 55.41 | 54.87 | 52.71 |
| Other cardiovascular hospitalization | 2088.85 | 2092.70 | 2103.60 |
| Bleeding events | |||
| Hemorrhagic stroke | 22.27 | 23.67 | 28.99 |
| Other intracranial hemorrhage | 6.85 | 7.35 | 9.24 |
| Other major bleeds | 815 | 820 | 838 |
| Clinically relevant non-major bleeds | 184 | 197 | 245 |
| Life years | |||
| Quality adjusted life years | 69,994 | 70,025 | 70,125 |
AF atrial fibrillation, ECG electrocardiogram, Z14 Zenicor screening for 14 days
Note: results are from a cohort of 10,000 patients 75 years of age followed for a lifetime who were screened for AF with the reported strategy at age 75 years