. 2020 Jul 9;20(10):58. doi: 10.1007/s11882-020-00954-0

Table 2.

Diagnostic sensitivity of Ves v 5 and Ves v 1 in diagnosis of patients with a history of yellow jacket venom allergy

Patients	Sensitivity YJV	Sensitivity Ves v 5	Sensitivity Ves v 5/Ves v 1	Method^a	Remarks	Reference
100	91% (91)^b	89% (89)	n.d.	ADVIA Centaur^d		[39]
91	IC sIgE	96% (87)	n.d.	ADVIA Centaur^d		[39]
59	86% (51)^b	90% (53)	n.d.	ImmunoCAP		[40]
32	IC sIgE	94% (30)	n.d.		ms
19	IC sIgE	95% (18)	n.d.		ds
8	IC neg.^b	63% (5)	n.d.
22	IC sIgE	n.s.	100% (22)	ImmunoCAP	ms	[51]
200	IC sIgE	85% (169)	92% (184)	ImmunoCAP	ms	[43]
163	n.s.	92% (150)	96% (156)	ImmunoCAP		[50]
26	IC neg.^b	65% (17)	65% (17)	ImmunoCAP		[50]
308	83% (257)^b	90% (277)	96% (296)	ImmunoCAP		[20••]
308	97% (298)^c	90% (277)	96% (296)	ImmunoCAP		[20••]
148	89% (131)^b	89% (131)	94% (139)	ImmunoCAP		[42]
91	IC sIgE	90% (82)	98% (89)		ms
17	IC neg.^b	71% (12)	71% (12)
170	IC sIgE	93% (158)	n.d.	ImmunoCAP		[41]
103	IC sIgE	92% (95)	n.d.		ms
67	IC sIgE	94% (63)	n.d.		ds
43	IC sIgE	98% (42)	n.d.	ImmunoCAP		[32••]
111	100% (111)	87% (96)	98% (109)	ImmunoCAP		[45]
111	98% (109)	92% (102)	n.d.	Immulite		[45]
110	IC sIgE	82% (90)	90% (99)	ImmunoCAP	ms	[44]
110	IC sIgE	93% (102)	97% (107)	Immulite/ImmunoCAP	ms	[44]
25	92% (23)^b	92% (23)	100% (25)	Immulite		[49]
49^e	88% (43)^b	86% (42)	92% (45)	Immulite		[49]

n.d. not determined, n.s. not shown, IC sIgE sIgE to YJV ≥ 0.35 kU_A/L was inclusion criterion, IC neg. sIgE to YJV < 0.35 kU_A/L was inclusion criterion, ms yellow jacket venom-monosensitized, ds yellow jacket venom and honeybee venom-double-sensitized

^aValues ≥ 0.35 kU_A/L were considered positive

^bYJV extract not spiked with Ves v 5 was used for measurement

^cYJV extract spiked with Ves v 5 was used for measurement

^dNo longer available

^ePatients with mastocytosis and/or elevated baseline serum tryptase