Table 3.
Baseline characteristics of fevered COVID-19 patients with different severity.
| Non-severe | Severe | P-value | |
|---|---|---|---|
| (n = 130) | (n = 45) | ||
| Sex (male/female) | 64/66 | 26/19 | 0.323 |
| Age, median (range), y | 42 (21–84) | 57 (25–75) | 0.000 |
| Tobacco (n, %) | 10 (7.7) | 2 (4.4) | 0.689 |
| Alcohol (n, %) | 4 (3.1) | 3 (6.7) | 0.537 |
| Comorbidities | |||
| Hypertension (n, %) | 13 (10.0) | 15 (33.3) | 0.000 |
| Cardiovascular disease (n, %) | 2 (1.5) | 5 (11.1) | 0.017 |
| Diabetes (n, %) | 7 (5.4) | 4 (8.9) | 0.632 |
| COPD, (n, %) | 0 (0.0) | 1 (2.2) | 0.257 |
| Cerebrovascular disease (n, %) | 4 (3.1) | 2 (4.4) | 0.648 |
| Chronic liver disease (n, %) | 7 (5.4) | 3 (6.7) | 1.000 |
| Malignancy (n, %) | 0 (0.0) | 0 (0.0) | NA |
| Symptoms | |||
| Respiratory symptom (n, %) | 110 (84.6) | 45 (100.0) | 0.005 |
| Digestive symptom (n, %) | 86 (66.2) | 33 (73.3) | 0.374 |
| Chest CT positive rate (n, %) | 125 (96.2) | 45 (100.0) | 0.330 |
| Chest CT with ground-glass change | 55 (42.3) | 31 (68.9) | 0.002 |
| Respiratory support | |||
| Non-invasive ventilation (n, %) | 0 (0.0) | 4 (8.9) | 0.004 |
| High-flow oxygen therapy (n, %) | 0 (0.0) | 13 (28.9) | 0.000 |
| Invasive ventilation (n, %) | 0 (0.0) | 4 (8.9) | 0.004 |
| ECMO (n, %) | 0 (0.0) | 3 (6.7) | 0.016 |
| Prognostic indicators | |||
| Length of hospital stay, median (range), days | 15.5 (5.0-41.0) | 21.0 (8.0–41.0) | 0.007 |
| Virus shedding duration, median (range), days | 16.5 (6.0-53.0) | 21.0 (12.0–59.0) | 0.002 |
| Mortality (n, %) | 0 (0.0) | 2 (4.4) | 0.065 |
P < 0.05 was considered statistically significant (marked in bold). Continuous variables were described as median with range and analyzed by Mann-Whitney test. Categorical variables were described as percentages and analyzed by the χ2 test or Fisher's exact test.
Abbreviations: COVID-19, coronavirus disease 2019; COPD, chronic obstructive pulmonary disease; ECMO, extracorporeal membrane oxygenation. NA, not applicable.