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. 2020 Jun;9(3):653–660. doi: 10.21037/gs.2020.04.03

Table 3. TI-RADS diagnostic efficiency (%).

TI-RADS No. of nodules Sensitivity Specificity Youden’s index Positive predictive value Negative predictive value
Benign Malignant
2 31 2 99.75 6.13 5.87 62.24 93.94
3 358 39 94.78 76.88 71.65 86.41 90.47
4a 66 45 89.04 89.92 78.97 93.20 84.10
4a-4b 7 15 87.13 91.30 78.44 93.96 82.06
4b 30 123 71.46 97.23 68.70 97.57 68.72
4b-4c 4 50 65.10 98.02 63.12 98.08 64.42
4c 10 340 21.78 100.00 21.78 100.00 45.18
4c-5 0 3 21.40 100.00 21.40 100.00 45.06
5 0 167 0.13 100.00 0.13 100.00 39.22

TI-RADS, thyroid imaging-reporting and data system.