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. 2020 Jul 9;10:11380. doi: 10.1038/s41598-020-68397-1

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Organotypic brain slices (350-µm thick) treated for 1 h with the vehicles, G-AuNPs and DG-AuNPs (0.7 mg/mL) and irradiated with pulsed laser tuned at 760 nm at various power. DAPI was used to identify cell nuclei, and PI for cell death. Dotted circles represent heat-formed bubbles generated soon after irradiation. Scale bar: 50 µm.