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. 2020 Jul 9;11:3419. doi: 10.1038/s41467-020-17065-z

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a Genome-browser snapshot of a contact domain on chromosome 13 as in Fig. 2a displaying the ChIP-seq profiles of H3K27ac in the P7 and P60 cerebellum. Also displayed is the ChIP-seq profile of H3K27ac in the cerebellum of control and Chd4 cKO mice at P60. Blue denotes the extent of the contact domain. b, c Density plot comparing the change in Hi-C contacts within a domain with the (b) change in H3K27ac in the cerebellum between P7 and P60 and (c) change in H3K27ac in the cerebellum of control and Chd4 cKO mice at P60. Pearson’s r, p < 0.001.