Table 2.

Consumption of volatile anesthetic guided by BIS or standard practice by anesthesia time.

Group	BIS (mL/h)	Standard practice (mL/h)	P
Sevoflurane (median [25–75% interquartile values])
	10.5 (8.7–13.0), n = 1,324	11.4(9.0–14.5), n = 3,819	< 0.001
Desflurane (median [25–75% interquartile values])
	17.4(13.7–21.1), n = 378	20.2(15.8–25.0), n = 1,192	< 0.001
Sevoflurane (mean [95% CI])
2 h	11.5(11.2–11.7) , n = 1,324	12.3(12.2–12.5) , n = 3,819	< 0.001
4 h	11.2(10.9–11.4) , n = 1,102	12.0(11.94–12.2) , n = 2,759	< 0.001
6 h	10.6(10.2–10.9) , n = 529	11.7(11.4–12.0) , n = 992	< 0.001
8 h	10.1(9.6–10.6) , n = 255	11.0(10.5–11.5) , n = 347	0.016
≥ 10 h	9.4(8.9–9.9) , n = 123	10.0(9.3–10.8) , n = 155	0.160
Desflurane (mean [95% CI])
2 h	18.3(17.6–19.0), n = 378	20.9(20.5–21.4), n = 1,192	< 0.001
4 h	18.2(17.4–19.0), n = 332	20.8(20.3–21.3) , n = 944	< 0.001
6 h	17.2(16.2–18.2) , n = 161	19.0(18.1–19.8) , n = 279	0.009
8 h	17.5(15.9–19.1) , n = 63	18.0(16.5–19.6) , n = 91	0.643
≥ 10 h	16.4(13.5–19.2) , n = 20	17.9(15.3–20.5) , n = 36	0.433

Data were expressed as median (25–75% interquartile values) or mean (95% CI).