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. 2020 Jul 3;11:1401. doi: 10.3389/fmicb.2020.01401

TABLE 2.

Trends of fluconazole and voriconazole resistance or non-wild-type phenotype in Candida species over 10 years.

Resistance (%)
2010 2011 2012 2013 2014 2015 2016 2017 2018 2019
Fluconazole
C. albicans 0.0 5.1 3.0 0.0 5.6 0.0 0.0 6.7 5.9 0.0
C. parapsilosis complex 0.0 0.0 5.9 0.0 0.0 0.0 0.0 9.1 0.0 0.0
C. tropicalis 25.0 36.4 16.7 12.5 40.0 60.0 50.0 75.0 35.7 50.0
C. glabrata 22.2 35.7 33.3 40.0 18.2 25.0 33.3 0.0 0.0 0.0
C. krusei 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0
Voriconazole
C. albicans 0.0 5.1 0.0 0.0 0.0 0.0 0.0 6.7 2.9 0.0
C. parapsilosis complex 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
C. tropicalis 8.3 18.2 0.0 12.5 40.0 40.0 50.0 75.0 35.7 33.3
C. glabrata 88.9 71.4 66.7 60.0 36.4 50.0 66.7 0.0 0.0 100.0
C. krusei 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.0 0.0