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. 2020 Jul 3;10:1272. doi: 10.3389/fonc.2020.01272

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Copyright © 2020 Ye, Xiao, Li, Zhu, Li, Wu, Huang, Jin, Chen, Jin and Huang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The clinical characteristics and treatment of a COVID-19 patient with chronic lymphocytic leukemia (CLL) (I-2) from a familial cluster during 69 days of follow-up. (A) Genealogical tree of patient I-2. (B) Chest CT of patient I-2 on day -7 (a1,a2), day 1 (b1,b2,b3), day 8 (c1,c2), day 18 (d1,d2), day 26 (e1,e2), day 35 (f1,f2), and day 47 (g1,g2). (C) Peripheral blood smear of patient I-2 (Wright's staining, oil-immersion lens, 1,000 ×). (D) Immunophenotyping of peripheral blood cells of patient I-2. (E) Time at home or in hospital, clinical symptoms, positive or negative novel coronavirus nucleic acid result, and the use of antiviral drugs and immune modulators for 69 days of follow-up of patients I-2, I-1, and II-3. a-2b: interferon α-2b, IVIG: intravenous immunoglobulin.