FIGURE 6.

UHRF1‐related genes in ADC could predict the survival and pathological status of ADC patients. A, The gene signature expression in survivors and non‐survivors; B, The gene signature expression in different pathological stages; C, Kaplan‐Meier plot in ADC discovery and validation cohort; D, Kaplan‐Meier plot in ADC validation cohort; E, H1975 and S‐MES‐1 cells were transfected with siRNA‐UHRF1‐1 and FACS analysis was performed to detect the cell cycle distribution; F, The H1975 and S‐MES‐1 cells were transfected with siRNA‐UHRF1‐1 and then treatment with docetaxel, and FACS analysis was performed to detect the cell apoptosis, * and *** indicated P < .05 and P < .001, respectively