Figure 4.

MiR‐126a‐5p agomirs limits AAA formation in vivo. AAA mice were treated with miR‐126a‐5p agomirs or NC agomirs, and on day 28 post‐Ang II treatment, all mice were killed. Representative ultrasound images (longitudinal view) showing suprarenal aortas of Apoe^‐/‐ mice, and the maximal aortic diameters were recorded (A, left; B). Whole mouse aortas were shown in A (right). Values were presented as means ± SEM (n = 5). ^††† P < .001. Aortas were stained via H&E (C; Bar, 500 μm), and EVG (D; Bar, 100 μm). The deposition of collagens was probed with Sirius red (E; Bar, 50 μm). ^††† P < .001