Table 1.

Procedures and comparison of the standard of care and intervention arms in the parent randomised controlled trial of extended ART refills^12–15

	Standard of care: 2-month refill adherence clubs	Intervention: 6-month refill adherence clubs
Eligibility	Eligibility for adherence club care Adults over 18 years On the same ART regimen for at least 6 months Undetectable VL No current tuberculosis or pregnancy or condition requiring regular clinical follow-up All participants were previously enrolled in an adherence club care at Site B Community Health Centre
Adherence club visits	Frequency: Two monthly (four visits receiving 2-month ART refills and one visit receiving 4-month ART refills over the December holiday period) (five per year)	Frequency: Six monthly (two per year)
	Provider: Led by club facilitator (lay counsellor)
	Location: In the community (such as a library or community hall) or the facility
Routine bloods (VL and for clinical review, depending on the regimen)	Frequency: Twelve monthly
	Provider: Managed by a nurse
	Location: At the facility, part of the adherence club visit	Location: At the facility, an additional individual visit, scheduled 1 month before the adherence club visit
Clinical consultations	Frequency: Twelve monthly
	Provider: Managed by a nurse
	Location: At the facility (part of the adherence club visit)
Grace period	Patients can collect medication up to 5 days after their scheduled appointment
Treatment ‘buddies’	Allowed to collect on a patient’s behalf at every other visit	Not permitted

ART, antiretroviral treatment; VL, viral load.