Fig. 2.

Heat maps and fold change of differentially expressed genes in primary human lung epithelial cells infected with MERS-CoV or SARS-CoV-2. Total RNA was collected from primary human lung epithelial cells infected with MERS-CoV or SARS-CoV-2 at 12 hours p.i. The purified RNA was used for microarray analysis using a human DNA chip. A. The number of differentially expressed genes with more than a twofold change in expression in human lung cells compared to those in uninfected human lung cells. B. Description of genes commonly modulated in human lung cells infected with MERS-CoV and SARS-CoV-2. C. Heat map of all genes with more than a twofold change in expression in human lung cells infected with MERS-CoV compared to those in uninfected human lung cells. D. Heat map of all genes with more than a twofold change in expression in human lung cells infected with SARS-CoV-2 compared to those in uninfected human lung cells